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David Anderson2023-12-20 16:26:052023-12-20 16:43:11Dr. Erba discusses the KOMET-001 Phase 1b safety and tolerability data of ziftomenib, a menin inhibitor, for patients with R/R NPM1-m AML
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David Anderson2023-12-19 16:47:432023-12-20 16:48:26Dr. Erba offers insight into the KOMET-007 Phase 1 trial and rationale for investigating ziftomenib in combination with standards of care for the treatment of patients with newly diagnosed or R/R NPM1-m or KMT2A-r AML
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David Anderson2023-12-18 16:50:412023-12-20 16:50:53Dr. Erba explains the different combinations KOMET-008 will evaluate and how it differs from KOMET-007
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David Anderson2023-12-17 16:52:422023-12-20 16:52:53“Project Optimus encourages optimal biological dosing rather than maximally tolerated dosing.” — Harry Erba, MD, PhD
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David Anderson2023-12-16 16:56:012023-12-20 16:56:13Dr. Erba provides an overview of the KOMET clinical trial program
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David Anderson2023-08-23 17:17:322023-08-24 08:43:04Evaluating ziftomenib in combinations for patients who are newly diagnosed or relapsed/refractory NPM1m or KMT2Ar AML
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eallison2023-06-16 13:46:022023-08-23 17:46:15Emerging advancements in acute myeloid leukemia
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eallison2023-06-16 13:47:032023-08-23 17:06:30Can you give a brief overview of unmet medical needs within NPM1-mutated acute myeloid leukemia?
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eallison2023-08-08 16:40:522023-08-23 17:06:48NPM1 mutations in acute myeloid leukemia: actionable mutations to inform treatment decisions with clinical trials
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eallison2023-08-08 16:12:302023-08-23 17:07:13Mechanism of action for investigational menin inhibitors, including ziftomenib
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